The two dont have to be mutually exclusive, but any peptide therapy in this context needs to account for the full hormonal picture, thyroid, cortisol, estrogen, not just body weight
Melatonin accelerates the phase shift if given at the appropriate time prior to bedtime at destination, and the benefits of melatonin administration in the alleviation of jet lag seems to be greater with larger numbers of time zones (105)
Ozcan, K., Kopf, M., Thompson, A
For example, after lowering your dose to the lowest available one, you may go from taking injections weekly, to every other week, then to every three weeks
Finally, GSH is also a cofactor for several antioxidant enzymes